BGC > Product Search > N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine | 139504-50-0
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Suppliers for CAS
139504-50-0
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Properties | | CAS |
139504-50-0 | | Formula |
C35H48ClN3O10S |
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9 Registered suppliers
Amadis Chemical Company Limited
P.R.China
Hangzhou Keying Chem Co., Ltd.
P.R.China
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C35H48ClN3O10S
Molecular Weight: 738.28772
Shandong Ench Chemical Co.,Ltd
P.R.China
| Appearance | white powder
| | Purity | 99% min |
Maytansine DM1 is a tubulin inhibitor that binds to the ends of microtubules and inhibits the dynamics of microtubules.
Used as the cytotoxic component of antibody-drug conjugates.
Aea.ltd
P.R.China
| Appearance | white powder
| | Purity | 99% min |
Maytansine DM1 is a tubulin inhibitor that binds to the ends of microtubules and inhibits the dynamics of microtubules.
Used as the cytotoxic component of antibody-drug conjugates.
Hangzhou Lingrui Chemical Co., Ltd.
P.R.China
| Appearance | white powder
| | Purity | 99% min |
Maytansine DM1 is a tubulin inhibitor that binds to the ends of microtubules and inhibits the dynamics of microtubules.
Used as the cytotoxic component of antibody-drug conjugates.
BOC Sciences
USA
Description : Mertansine, the cytotoxic component in antibody-drug conjugates, is attached to a monoclonal antibody through reaction of the thiol group with the SPP (N-succinimidyl 4-(2-pyridyldithio)) linker or SMCC (4-(3-mercapto-2,5-dioxo-1 pyrrolidinylmethyl)-cylohexanecarboxylic acid) linkerto create an antibody-drug conjugate. It derives from a maytansine. - Molecular Weight :738.29
- Boiling Point :937.1±65.0 °C Press: 760 Torr
- Melting Point :> 168°C (dec.)
- Purity :≥95%
Molecular Formula : C35H48ClN3O10S Canonical SMILES : CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)OC(=O)C(C)N(C)C(=O)CCS)C)C)OC)(NC(=O)O2)O
InChI :
InChI=1S/C35H48ClN3O10S/c1-19-10-9-11-26(46-8)35(44)18-25(47-33(43)37-35)20(2)31-34(4,49-31)27(48-32(42)21(3)38(5)28(40)12-13-50)17-29(41)39(6)23-15-22(14-19)16-24(45-7)30(23)36/h9-11,15-16,20-21,25-27,31,44,50H,12-14,17-18H2,1-8H3,(H,37,43)/b11-9+,19-10+/t20-,21+,25+,26-,27+,31+,34+,35+/m1/s1
InChIKey :
ANZJBCHSOXCCRQ-FKUXLPTCSA-N
Solubility :
Soluble in chloroform (slightly), methanol (slightly)
Appearance :
White to light yellow solid
Storage : Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Synonyms :
(14S,16S,33S,2R,4R,10E,12Z,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-(3-mercaptopropanoyl)-N-methyl-L-alaninate; N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine; DM 1; Maytansinoid DM 1; N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine; DM-1; DM1; DM1 Compound; DM1 [Maytansinoid]
More details are to be found here
Autech Industry Co.,Limited
P.R.China
Description : Mertansine, the cytotoxic component in antibody-drug conjugates, is attached to a monoclonal antibody through reaction of the thiol group with the SPP (N-succinimidyl 4-(2-pyridyldithio)) linker or SMCC (4-(3-mercapto-2,5-dioxo-1 pyrrolidinylmethyl)-cylohexanecarboxylic acid) linkerto create an antibody-drug conjugate. It derives from a maytansine. - Molecular Weight :738.29
- Boiling Point :937.1±65.0 °C Press: 760 Torr
- Melting Point :> 168°C (dec.)
- Purity :≥95%
Molecular Formula : C35H48ClN3O10S Canonical SMILES : CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)OC(=O)C(C)N(C)C(=O)CCS)C)C)OC)(NC(=O)O2)O
InChI :
InChI=1S/C35H48ClN3O10S/c1-19-10-9-11-26(46-8)35(44)18-25(47-33(43)37-35)20(2)31-34(4,49-31)27(48-32(42)21(3)38(5)28(40)12-13-50)17-29(41)39(6)23-15-22(14-19)16-24(45-7)30(23)36/h9-11,15-16,20-21,25-27,31,44,50H,12-14,17-18H2,1-8H3,(H,37,43)/b11-9+,19-10+/t20-,21+,25+,26-,27+,31+,34+,35+/m1/s1
InChIKey :
ANZJBCHSOXCCRQ-FKUXLPTCSA-N
Solubility :
Soluble in chloroform (slightly), methanol (slightly)
Appearance :
White to light yellow solid
Storage : Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Synonyms :
(14S,16S,33S,2R,4R,10E,12Z,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-(3-mercaptopropanoyl)-N-methyl-L-alaninate; N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine; DM 1; Maytansinoid DM 1; N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine; DM-1; DM1; DM1 Compound; DM1 [Maytansinoid]
More details are to be found here
Chemlyte Solutions
P.R.China
More details are to be found here
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