BGC > Product Search > Selinexor | 1393477-72-9

Molecular Formula: C17H11F6N7O
Molecular Weight: 443.3059592

Molecular Formula: C17H11F6N7O
Molecular Weight: 443.3059592

Molecular Formula: C17H11F6N7O
Molecular Weight: 443.3059592

Description :
Selinexor is a potent and selective inhibitor of chromosome region maintenance 1 protein/exportin 1 (CRM1/XPO1). Selinexor was studied to show in vivo anti-leukaemic efficacy against T-ALL and acute myeloid leukaemia (AML) cells.

• Molecular Weight :443.31
• Purity :≥95%

Molecular Formula :
C17H11F6N7O
Canonical SMILES :
C1=CN=C(C=N1)NNC(=O)C=CN2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F
InChI :
InChI=1S/C17H11F6N7O/c18-16(19,20)11-5-10(6-12(7-11)17(21,22)23)15-26-9-30(29-15)4-1-14(31)28-27-13-8-24-2-3-25-13/h1-9H,(H,25,27)(H,28,31)/b4-1-
InChIKey :
DEVSOMFAQLZNKR-RJRFIUFISA-N
Solubility :
Soluble in DMSO, Ethanol
Appearance :
Off-white Solid
Storage : Store at -20°C
Synonyms :
KPT-330; KPT 330; KPT330; 2-Propenoic acid, 3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-, 2-(2-pyrazinyl)hydrazide, (2Z)-; Xpovio; (Z)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide; (2Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-propenoic acid 2-(2-pyrazinyl)hydrazide

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