|
|
Suppliers for
SCH772984
|
Properties | CAS |
942183-80-4 | Formula |
C33H33N9O2 |
|
|
3 Registered suppliers
Molecular Formula: C33H33N9O2 Molecular Weight: 587.685 HS Code: 29339900
Molecular Formula: C33H33N9O2 Molecular Weight: 587.685 HS Code: 29339900
Description : SCH772984 is a potent and selective ERK inhibitor with potential anticancer activity. SCH722984 showed activity against BRAF mutant, NRAS mutant and wild-type melanoma. Combining vemurafenib and SCH722984 in BRAF mutant melanoma was synergistic in a majority of cell lines and significantly delayed the onset of acquired resistance in long term in vitro assays. Therefore, SCH772984 may be clinically applicable as a treatment for non-BRAF mutant melanoma or in BRAF-mutant melanoma with innate or acquired resistance, alone or in combination with BRAF inhibitors. - Molecular Weight :587.688
- Boiling Point :857.3±65.0 °C at 760 mmHg
- Purity :95%
Molecular Formula : C33H33N9O2 Canonical SMILES : C1CN(CC1C(=O)NC2=CC3=C(C=C2)NN=C3C4=CC=NC=C4)CC(=O)N5CCN(CC5)C6=CC=C(C=C6)C7=NC=CC=N7 InChI : InChI=1S/C33H33N9O2/c43-30(42-18-16-41(17-19-42)27-5-2-24(3-6-27)32-35-11-1-12-36-32)22-40-15-10-25(21-40)33(44)37-26-4-7-29-28(20-26)31(39-38-29)23-8-13-34-14-9-23/h1-9,11-14,20,25H,10,15-19,21-22H2,(H,37,44)(H,38,39)/t25-/m1/s1 InChIKey : HDAJDNHIBCDLQF-RUZDIDTESA-N Appearance : Solid powder Synonyms : SCH-772984; SCH 772984; (R)-1-(2-oxo-2-(4-(4-(pyrimidin-2-yl)phenyl)piperazin-1-yl)ethyl)-N-(3-(pyridin-4-yl)-1H-indazol-5-yl)pyrrolidine-3-carboxamide
More details are to be found here
Detailed information on the suppliers of
SCH772984
|
Properties:
... more properties and specification on SCH772984
|
|
Privileged suppliers
Last update 2024-05-28
|