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Suppliers for
Parecoxib Impurity 14
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Properties | CAS |
1708094-99-8 |
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2 Registered suppliers
Description : An impurity of Parecoxib. The prodrug Parecoxib as well as its active metabolite val have a specific affinity to the cannabinoid (CB) receptor measured in CB1-expressing HEK 293 cells and rat brain tissue. Adult male Sprague-Dawley rats were administered parecoxib (10 or 30 mg kg(-1), IP) or isotonic saline twice a day starting 24 h after middle cerebral artery occlusion (MCAO) for three consecutive days. The selective COX-2 inhibitor parecoxib was delivered 20 min before or 20 min after the incision by intraperitoneal injection. Pretreatment with parecoxib markedly attenuated the pain hypersensitivity induced by incision. - Molecular Weight :505.56
- Purity :95%
Molecular Formula : C22H23N3O7S2 Canonical SMILES : CCC(=O)NS(=O)(=O)C1=CC=C(C=C1)C2=C(ON=C2C3=CC(=CC=C3)S(=O)(=O)NC(=O)CC)C InChI : InChI=1S/C22H23N3O7S2/c1-4-19(26)24-33(28,29)17-11-9-15(10-12-17)21-14(3)32-23-22(21)16-7-6-8-18(13-16)34(30,31)25-20(27)5-2/h6-13H,4-5H2,1-3H3,(H,24,26)(H,25,27) InChIKey : CEAGKTBVTHYQAP-UHFFFAOYSA-N Solubility : Soluble in DMSO Appearance : Solid Storage : -20°C Synonyms : Valdecoxib Disulfonamide Impurity; Parecoxib Impurity H
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Last update 2024-05-28
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