BGC > Product Search > PF-06749305 | 1341224-83-6

Molecular Formula: C29H31F3N6O3

Molecular Formula: C29H31F3N6O3

Description :
PF-4136309 is a potent, selective, and orally bioavailable antagonist of CCR2, a chemokine receptor of the super family of seven-transmembrane G-protein-coupled receptors (GPCRs).

• Molecular Weight :568.59

Molecular Formula :
C29H31F3N6O3
Canonical SMILES :
C1CC(CCC1NC2CCN(C2)C(=O)CNC(=O)C3=CC(=CC=C3)C(F)(F)F)(C4=NC=C(C=C4)C5=NC=CC=N5)O
InChI :
InChI=1S/C29H31F3N6O3/c30-29(31,32)21-4-1-3-19(15-21)27(40)36-17-25(39)38-14-9-23(18-38)37-22-7-10-28(41,11-8-22)24-6-5-20(16-35-24)26-33-12-2-13-34-26/h1-6,12-13,15-16,22-23,37,41H,7-11,14,17-18H2,(H,36,40)/t22?,23-,28?/m0/s1
InChIKey :
ZNSVOHSYDRPBGI-CBQRAPNFSA-N
Solubility :
10 mM in DMSO.
Appearance :
Solid Powder
Synonyms :
(S)-N-(2-(3-((4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide; PF4136309; PF 4136309; PF04136309; PF-04136309; INCB8761; INCB 8761; INCB-8761

More details are to be found here