BGC > Product Search > P-[2-[[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]amino]-2-oxoethyl]phosphonic acid diethyl ester | 618061-76-0

Molecular Formula: C24H27ClFN4O6P
Molecular Weight: 553

Molecular Formula: C24H27ClFN4O6P
Molecular Weight: 553

Description :
Afatinib Impurity 52 is an impurity of Afatinib, a drug used to treat non-small cell lung cancer (NSCLC).

• Molecular Weight :552.92
• Boiling Point :709.9±60.0 °C at 760 mmHg
• Purity :95%

Molecular Formula :
C24H27ClFN4O6P
Canonical SMILES :
CCOP(=O)(CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4)OCC
InChI :
InChI=1S/C24H27ClFN4O6P/c1-3-34-37(32,35-4-2)13-23(31)30-21-10-17-20(11-22(21)36-16-7-8-33-12-16)27-14-28-24(17)29-15-5-6-19(26)18(25)9-15/h5-6,9-11,14,16H,3-4,7-8,12-13H2,1-2H3,(H,30,31)(H,27,28,29)/t16-/m0/s1
InChIKey :
FNGRCLBEXKFSST-INIZCTEOSA-N
Synonyms :
(S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate; Diethyl {[4-(3-Chloro-4-Fluoro-Phenylamino)-7-((S)-Tetrahydrofuran-3-Yloxy)-Quinazolin-6-Ylcarbamoyl]-Methyl}-Phosphonate

More details are to be found here