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Suppliers for CAS
1095173-27-5
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Properties | | CAS |
1095173-27-5 | | Formula |
C21H22N6O |
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4 Registered suppliers
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C21H22N6O
Molecular Weight: 374.43898
Molecular Formula: C21H22N6O
Molecular Weight: 374.43898
Aea.ltd
P.R.China
Molecular Formula: C21H22N6O
Molecular Weight: 374.43898
Molecular Formula: C21H22N6O
Molecular Weight: 374.43898
BOC Sciences
USA
Description : Glasdegib is an orally bioavailable small-molecule inhibitor of the Hedgehog (Hh) signaling pathway that binds to Smoothened (Smo) and inhibits signal transduction. It has been shown to attenuate leukemia stem cell self-renewal and cell cycle progression in primary acute myeloid leukemia cells and in an in vivo Drosophila model. - Molecular Weight :374.44
- Boiling Point :633.4±55.0 °C at 760 mmHg
- Melting Point :> 214 ºC
- Purity :> 98%
Molecular Formula : C21H22N6O Canonical SMILES : CN1CCC(CC1C2=NC3=CC=CC=C3N2)NC(=O)NC4=CC=C(C=C4)C#N
InChI :
InChI=1S/C21H22N6O/c1-27-11-10-16(24-21(28)23-15-8-6-14(13-22)7-9-15)12-19(27)20-25-17-4-2-3-5-18(17)26-20/h2-9,16,19H,10-12H2,1H3,(H,25,26)(H2,23,24,28)/t16-,19-/m1/s1
InChIKey :
SFNSLLSYNZWZQG-VQIMIIECSA-N
Appearance :
White Solid
Synonyms :
PF-04449913; PF 04449913; 1-[(2R,4R)-2-(1H-benzimidazol-2-yl)-1-methylpiperidin-4-yl]-3-(4-cyanophenyl)urea
More details are to be found here
Chemtour Biotech Co., Ltd
P.R.China
Description : Glasdegib is an orally bioavailable small-molecule inhibitor of the Hedgehog (Hh) signaling pathway that binds to Smoothened (Smo) and inhibits signal transduction. It has been shown to attenuate leukemia stem cell self-renewal and cell cycle progression in primary acute myeloid leukemia cells and in an in vivo Drosophila model. - Molecular Weight :374.44
- Boiling Point :633.4±55.0 °C at 760 mmHg
- Melting Point :> 214 ºC
- Purity :> 98%
Molecular Formula : C21H22N6O Canonical SMILES : CN1CCC(CC1C2=NC3=CC=CC=C3N2)NC(=O)NC4=CC=C(C=C4)C#N
InChI :
InChI=1S/C21H22N6O/c1-27-11-10-16(24-21(28)23-15-8-6-14(13-22)7-9-15)12-19(27)20-25-17-4-2-3-5-18(17)26-20/h2-9,16,19H,10-12H2,1H3,(H,25,26)(H2,23,24,28)/t16-,19-/m1/s1
InChIKey :
SFNSLLSYNZWZQG-VQIMIIECSA-N
Appearance :
White Solid
Synonyms :
PF-04449913; PF 04449913; 1-[(2R,4R)-2-(1H-benzimidazol-2-yl)-1-methylpiperidin-4-yl]-3-(4-cyanophenyl)urea
More details are to be found here
Detailed information on the suppliers of
Glasdegib |
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