Suppliers for CAS
1373215-15-6
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Properties | CAS |
1373215-15-6 | Formula |
C25H29FN4O5 |
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4 Registered suppliers
Amadis Chemical Company Limited
P.R.China
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C24H30N2O6 Molecular Weight: 442.5
Aea.ltd
P.R.China
Molecular Formula: C24H30N2O6 Molecular Weight: 442.5
BOC Sciences
USA
Description : Cathepsin S is expressed in antigen-presenting cells and plays a role in invariant chain processing and major histocompatibility complex class II (MHCII) antigen presentation leading to CD4+ T-cell activation. An oral Cathepsin S inhibitor that blocks MHCII antigen presentation could result in a T-cell-selective immunosuppressant agent with improved safety over the current standard of care for the treatment of rheumatoid arthritis, psoriasis, multiple sclerosis and other autoimmune-based inflammatory diseases. - Molecular Weight :484.52
- Purity :> 98%
Molecular Formula : C25H29FN4O5 Canonical SMILES : CNC(=O)OC1COC2=C(C1NC(=O)C3=CC=C(C=C3)F)C=C(C=C2)N4CCN(CC4)C5COC5 InChI : InChI=1S/C25H29FN4O5/c1-27-25(32)35-22-15-34-21-7-6-18(29-8-10-30(11-9-29)19-13-33-14-19)12-20(21)23(22)28-24(31)16-2-4-17(26)5-3-16/h2-7,12,19,22-23H,8-11,13-15H2,1H3,(H,27,32)(H,28,31)/t22-,23-/m0/s1 InChIKey : NDEBZCZEAVMSQF-GOTSBHOMSA-N Synonyms : LY3000328; LY-3000328; LY 3000328. Cathepsin S inhibitor
More details are to be found here
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