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BGC > Product Search > Cabazitaxel | 183133-96-2
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Suppliers for

Cabazitaxel



Properties

CAS   183133-96-2 
Formula   C45H57NO14 

Structure

17 Registered suppliers


Appearance   White or almost white crystalline powder
Identification   FT-IR ,HPLC
Water   3.0%
Melting Point   148 C—158 C
Residue on Ignition   ≤ 0.1%
Heavy metals   ≤ 20ppm
Residual Solvents  
Acetone   ≤ 5000ppm
Dichloromethane   ≤ 600ppm
n-Hexane   ≤ 290ppm
Acetic acid   ≤ 5000ppm
Ethyl acetate   ≤ 5000ppm
Tetrahydrofuran   ≤ 720ppm
Ethanol   ≤ 5000ppm
Related Substances  
Cabazitaxel   ≤ 0.3%
10-DABIII   ≤ 0.3%
Any other single impurity   ≤ 0.1%
Total impurities   ≤ 1.0%
Chromatographic purity(By HPLC)   ≥ 99.0%


Appearance   White or almost white crystalline powder
Identification   FT-IR ,HPLC
Water   3.0%
Melting Point   148 C—158 C
Residue on Ignition   ≤ 0.1%
Heavy metals   ≤ 20ppm
Residual Solvents  
Acetone   ≤ 5000ppm
Dichloromethane   ≤ 600ppm
n-Hexane   ≤ 290ppm
Acetic acid   ≤ 5000ppm
Ethyl acetate   ≤ 5000ppm
Tetrahydrofuran   ≤ 720ppm
Ethanol   ≤ 5000ppm
Related Substances  
Cabazitaxel   ≤ 0.3%
10-DABIII   ≤ 0.3%
Any other single impurity   ≤ 0.1%
Total impurities   ≤ 1.0%
Chromatographic purity(By HPLC)   ≥ 99.0%


Appearance   White or almost white crystalline powder
Identification   FT-IR ,HPLC
Water   3.0%
Melting Point   148 C—158 C
Residue on Ignition   ≤ 0.1%
Heavy metals   ≤ 20ppm
Residual Solvents  
Acetone   ≤ 5000ppm
Dichloromethane   ≤ 600ppm
n-Hexane   ≤ 290ppm
Acetic acid   ≤ 5000ppm
Ethyl acetate   ≤ 5000ppm
Tetrahydrofuran   ≤ 720ppm
Ethanol   ≤ 5000ppm
Related Substances  
Cabazitaxel   ≤ 0.3%
10-DABIII   ≤ 0.3%
Any other single impurity   ≤ 0.1%
Total impurities   ≤ 1.0%
Chromatographic purity(By HPLC)   ≥ 99.0%


Molecular Formula: C45H57NO14
Molecular Weight: 835.93238
HS Code: 29329990

More details are to be found here
Appearance   white powder
Purity   99% min
Application   Signal transduction pathway kinase inhibitor


Appearance   white powder
Purity   99% min
Application   Signal transduction pathway kinase inhibitor




More details are to be found here
Description :
Cabazitaxel increases CYP3A enzyme activities in rat hepatocytes. The mean ex-vivo human plasma protein binding of Cabazitaxel is 91.6%.
  • Molecular Weight :835.93
  • Melting Point :181-184°C
  • Purity :> 98%
Molecular Formula :
C45H57NO14
Canonical SMILES :
CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)OC)C)OC
InChI :
InChI=1S/C45H57NO14/c1-24-28(57-39(51)33(48)32(26-17-13-11-14-18-26)46-40(52)60-41(3,4)5)22-45(53)37(58-38(50)27-19-15-12-16-20-27)35-43(8,36(49)34(55-10)31(24)42(45,6)7)29(54-9)21-30-44(35,23-56-30)59-25(2)47/h11-20,28-30,32-35,37,48,53H,21-23H2,1-10H3,(H,46,52)/t28-,29-,30+,32-,33+,34+,35-,37-,43+,44-,45+/m0/s1
InChIKey :
BMQGVNUXMIRLCK-OAGWZNDDSA-N
Appearance :
White crystalline powder
Synonyms :
XRP6258; XRP-6258; XRP 6258; TXD 258; TXD-258; TXD258; RPR116258A; axoid XRP6258; dimethoxydocetaxel US brand name: Jevtana.

More details are to be found here
Description :
Cabazitaxel increases CYP3A enzyme activities in rat hepatocytes. The mean ex-vivo human plasma protein binding of Cabazitaxel is 91.6%.
  • Molecular Weight :835.93
  • Melting Point :181-184°C
  • Purity :> 98%
Molecular Formula :
C45H57NO14
Canonical SMILES :
CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)OC)C)OC
InChI :
InChI=1S/C45H57NO14/c1-24-28(57-39(51)33(48)32(26-17-13-11-14-18-26)46-40(52)60-41(3,4)5)22-45(53)37(58-38(50)27-19-15-12-16-20-27)35-43(8,36(49)34(55-10)31(24)42(45,6)7)29(54-9)21-30-44(35,23-56-30)59-25(2)47/h11-20,28-30,32-35,37,48,53H,21-23H2,1-10H3,(H,46,52)/t28-,29-,30+,32-,33+,34+,35-,37-,43+,44-,45+/m0/s1
InChIKey :
BMQGVNUXMIRLCK-OAGWZNDDSA-N
Appearance :
White crystalline powder
Synonyms :
XRP6258; XRP-6258; XRP 6258; TXD 258; TXD-258; TXD258; RPR116258A; axoid XRP6258; dimethoxydocetaxel US brand name: Jevtana.

More details are to be found here
Description :
Cabazitaxel increases CYP3A enzyme activities in rat hepatocytes. The mean ex-vivo human plasma protein binding of Cabazitaxel is 91.6%.
  • Molecular Weight :835.93
  • Melting Point :181-184°C
  • Purity :> 98%
Molecular Formula :
C45H57NO14
Canonical SMILES :
CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)OC)C)OC
InChI :
InChI=1S/C45H57NO14/c1-24-28(57-39(51)33(48)32(26-17-13-11-14-18-26)46-40(52)60-41(3,4)5)22-45(53)37(58-38(50)27-19-15-12-16-20-27)35-43(8,36(49)34(55-10)31(24)42(45,6)7)29(54-9)21-30-44(35,23-56-30)59-25(2)47/h11-20,28-30,32-35,37,48,53H,21-23H2,1-10H3,(H,46,52)/t28-,29-,30+,32-,33+,34+,35-,37-,43+,44-,45+/m0/s1
InChIKey :
BMQGVNUXMIRLCK-OAGWZNDDSA-N
Appearance :
White crystalline powder
Synonyms :
XRP6258; XRP-6258; XRP 6258; TXD 258; TXD-258; TXD258; RPR116258A; axoid XRP6258; dimethoxydocetaxel US brand name: Jevtana.

More details are to be found here

Detailed information on the suppliers of Cabazitaxel

Properties:

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