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Suppliers for
BI-3406
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Properties | CAS |
2230836-55-0 |
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5 Registered suppliers
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Description : BI-3406 is a potent and selective inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1). SOS1 is the guanine nucleotide exchange factor (GEF) and activator of RAS, and mutants of RAS are major oncogenes and occur in many human cancers. Inhibition of SOS1 in a mutant KRAS cell line can suppress tumor growth. Molecular Formula : C23H25F3N4O3 Canonical SMILES : CC1=NC2=CC(=C(C=C2C(=N1)NC(C)C3=CC(=CC(=C3)N)C(F)(F)F)OC4CCOC4)OC InChI : InChI=1S/C23H25F3N4O3/c1-12(14-6-15(23(24,25)26)8-16(27)7-14)28-22-18-9-21(33-17-4-5-32-11-17)20(31-3)10-19(18)29-13(2)30-22/h6-10,12,17H,4-5,11,27H2,1-3H3,(H,28,29,30)/t12-,17+/m1/s1 InChIKey : XVFDNRYZXDHTHT-PXAZEXFGSA-N Synonyms : BI 3406; BI3406
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BI-3406
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Properties:
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Last update 2024-05-28
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